Detalhe da pesquisa
1.
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
Nat Immunol
; 15(2): 152-60, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24317040
2.
CSL112 Infusion Rapidly Increases APOA1 Exchange Rate via Specific Serum Amyloid-Poor HDL Subpopulations When Administered to Patients Post-Myocardial Infarction.
Arterioscler Thromb Vasc Biol
; 43(6): 855-869, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36994730
3.
Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue.
J Hepatol
; 78(5): 901-913, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36717026
4.
ApoA-I Infusion Therapies Following Acute Coronary Syndrome: Past, Present, and Future.
Curr Atheroscler Rep
; 24(7): 585-597, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35524914
5.
Co-administration of CSL112 (apolipoprotein A-I [human]) with atorvastatin and alirocumab is not associated with increased hepatotoxic or toxicokinetic effects in rats.
Toxicol Appl Pharmacol
; 422: 115557, 2021 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33932462
6.
Pharmacometric analyses to characterize the effect of CSL112 on apolipoprotein A-I and cholesterol efflux capacity in acute myocardial infarction patients.
Br J Clin Pharmacol
; 87(6): 2558-2571, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33217027
7.
Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres: Effects of HDL Particle Remodeling on Cholesterol Efflux.
Arterioscler Thromb Vasc Biol
; 40(5): 1182-1194, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32131613
8.
CSL112 (Apolipoprotein A-I [Human]) Enhances Cholesterol Efflux Similarly in Healthy Individuals and Stable Atherosclerotic Disease Patients.
Arterioscler Thromb Vasc Biol
; 38(4): 953-963, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29437574
9.
A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.
J Immunol
; 198(10): 3775-3789, 2017 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28483986
10.
Circulating HDL levels control hypothalamic astrogliosis via apoA-I.
J Lipid Res
; 59(9): 1649-1659, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29991652
11.
Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity.
Circ Res
; 119(6): 751-63, 2016 Sep 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27436846
12.
Evaluation of potential antiplatelet effects of CSL112 (Apolipoprotein A-I [Human]) in patients with atherosclerosis: results from a phase 2a study.
J Thromb Thrombolysis
; 45(4): 469-476, 2018 May.
Artigo
Inglês
| MEDLINE | ID: mdl-29582212
13.
Reconstituted high-density lipoproteins acutely reduce soluble brain Aß levels in symptomatic APP/PS1 mice.
Biochim Biophys Acta
; 1862(5): 1027-36, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26454209
14.
Structure-function relationships in reconstituted HDL: Focus on antioxidative activity and cholesterol efflux capacity.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(9): 890-900, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28529180
15.
Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
J Immunol
; 195(1): 257-64, 2015 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26026058
16.
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature
; 464(7293): 1357-61, 2010 Apr 29.
Artigo
Inglês
| MEDLINE | ID: mdl-20428172
17.
Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component.
J Appl Toxicol
; 36(8): 1038-47, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-26651060
18.
CSL112 enhances biomarkers of reverse cholesterol transport after single and multiple infusions in healthy subjects.
Arterioscler Thromb Vasc Biol
; 34(9): 2106-14, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24969776
19.
Novel formulation of a reconstituted high-density lipoprotein (CSL112) dramatically enhances ABCA1-dependent cholesterol efflux.
Arterioscler Thromb Vasc Biol
; 33(9): 2202-11, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23868939
20.
11ß-HSD1 inhibition reduces atherosclerosis in mice by altering proinflammatory gene expression in the vasculature.
Physiol Genomics
; 45(1): 47-57, 2013 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23170035